Amakuru - Ni iki abakora bagomba kumenya ku ifu ya aside ya Alpha Lipoic?

Ifu ya aside ya Alpha Lipoic ni iki mu by'ukuri?

Acide Alpha Lipoic (ALA) ni ikintu gisanzwe kigira uruhare runini mu mubiri w'umuntu. Gikora nka coenzyme mu bikorwa byinshi bya mitochondrial, bishinzwe gutanga ingufu mu turemangingo. Bitandukanye n'intungamubiri zimwe na zimwe zigarukira ahantu runaka, ALA iboneka muri buri turemangingo, bigatuma iba ingenzi cyane mu kubungabunga imikorere myiza ya metabolisme.

Mu rwego rw'inganda, ifu ya ALA ikorwa binyuze mu buryo bugezweho bwo kuyikuramo no kuyivanga kugira ngo habeho ubuziranenge bwinshi no kuba iboneka neza. Ikunze gutangwa nk'ifu nziza, y'umuhondo woroshye, yoroshye kuyivangamo capsules, ibinini, ifu y'ibinyobwa, cyangwa ndetse n'utundi dufungurwa. Uku guhinduka ni imwe mu mpamvu zatumye ALA ikundwa cyane n'ibigo by'inyongeramusaruro.

Kuki aside Alpha Lipoic yitwa "Antioxidant rusange"?

Izina ry'ikinyabutabire rya ALA, "antioxidant isanzwe," rikomoka ku bushobozi bwayo bwihariye bwo gukora ahantu hashongera amazi n'ahashongera ibinure. Ibi bivuze ko ishobora kuzenguruka umubiri wose, ndetse no mu ngirabuzimafatizo, kugira ngo ihagarike uturemangingo twangiza aho tugaragara hose.

Byongeye kandi, ALA ntikora yonyine - ifite ubushobozi budasanzwe bwo kongera gukoresha izindi antioxydants. Urugero, iyo Vitamine C cyangwa Vitamine E ikoreshejwe mu kurwanya stress ya oxidative, ALA ishobora kubafasha kuyisubiza mu buryo bwayo bukora. Iyi miterere yo kongera ubushobozi bwo kongera imikorere y'urusobe rw'irwanya oxidative kandi igaha abakora iyo miti uburenganzira bukomeye bwo kwamamaza ibicuruzwa birimo ALA.

Ni gute ALA ishyigikira umusaruro w'ingufu?

Akamaro k'ibanze ka aside Alpha Lipoic mu gukora ingufu ni ugufasha imisemburo gusenya karubohidrati mo ingufu zikoreshwa. By'umwihariko, ikora nk'ikintu gihuza imiterere ya enzymes za mitochondrial zihindura glucose muri ATP - isoko y'ingufu z'uturemangingo.

Ku bakoresha, ibi bivuze ko ingufu zikoreshwa mu gutunganya neza no kugabanya umunaniro, cyane cyane ku bantu babaho mu buzima buhuze. Ku bakora, ibi bivuze ko ALA ishobora gushyirwa mu mwanya w’igisubizo karemano cyo gushyigikira ingufu mu nyongeramusaruro zigenewe abakozi bo mu biro, abanyeshuri, n’abantu bakora cyane. Uruhare rwayo rubiri nk’inyongeramusaruro ndetse n’inyongeramusaruro ituma iba amahitamo meza ku miti ikoreshwa mu buryo bwinshi.

Ese ALA ishobora gufasha mu gucunga urugero rwiza rw'isukari mu maraso?

Imwe mu nyungu za ALA zakoreweho ubushakashatsi cyane ni ingaruka zayo ku mikorere y'isukari mu mubiri. Yongera ubushobozi bwo kumva insuline, igafasha umubiri gukoresha isukari neza. Ibi bituma ingufu zihoraho umunsi wose kandi bigatuma pancreas igabanuka.

Ku nganda, ibi bitanga amahirwe yo kwamamaza ALA nk'igice cy'ibicuruzwa bishyigikira isukari mu maraso, imiterere y'umubiri, cyangwa inyongeramusaruro nziza zishaje. Ibi ni ibyiciro bikenerwa cyane kuko abaguzi bagenda barushaho gusobanukirwa akamaro ko kubungabunga urugero rwiza rw'isukari mu maraso kugira ngo hirindwe umunaniro n'ingorane z'igihe kirekire.

Kuki ALA ikunzwe cyane mu miti irwanya gusaza?

Umuvuduko wa okisidatike ni kimwe mu bintu by’ingenzi bitera gusaza kw’uturemangingo. Uko igihe kigenda gihita, kwangirika kw’uturemangingo tw’ubuntu bishobora kwirundanya no kugira ingaruka mbi ku ruhu, ku buzima bw’ubwonko, ndetse no ku buzima rusange. ALA irwanya ibi irinda uturemangingo kwangirika kwa okisidatike ndetse inashyigikira kuvugurura izindi antioxydants.

Inganda nyinshi zikora ALA mu bicuruzwa byagurishijwe nk' "ibirwanya gusaza imbere." Izi nyongeramusaruro zikurura abaguzi bashaka igisubizo cyuzuye gishyigikira uruhu, ubuzima bwo mu mutwe, n'ingufu icyarimwe. Iyi nyungu igamije ibintu byinshi ni isoko rikomeye ry'ubwiza n'imibereho myiza mu isoko ry'ubwiza rikomeje guhatana.

Ni iki gituma aside Alpha Lipoic iba yihariye ugereranyije n'izindi antioxydants?

Antioxydants nyinshi zishobora gushonga mu mazi cyangwa gushonga mu mavuta, bivuze ko zifite aho zigarukira aho zishobora gukora mu mubiri. Gushonga kabiri kwa ALA biyiha inyungu idasanzwe, bigatuma ikora mu mwanya wo mu ngirabuzima fatizo no mu mwanya wo hanze y’umubiri.

Iyi miterere idasanzwe kandi yemerera ALA kwambuka umupaka w’amaraso n’ubwonko, ari nayo mpamvu ikunze gushyirwa mu miti ifasha mu bumenyi bw’umubiri. Ku bakora iyi miti, bivuze ko ALA ishobora gutezwa imbere mu byiciro byinshi - kuva ku buzima bw’imikorere y’umubiri kugeza ku buzima bw’ubwonko kugeza ku buzima bw’uruhu - hatabayeho gukoresha ibintu bitandukanye kuri buri gikorwa.

Ese ALA ikwiriye amatsinda menshi y'abaguzi?

Kimwe mu byiza bikomeye bya ALA ni uko ikunzwe cyane. Abahanga bakiri bato bashobora kuyikoresha kugira ngo igire imbaraga n'ubushobozi bwo gutekereza neza, abakinnyi bashobora kuyiha agaciro kugira ngo yongere gukira, naho abantu bakuze bashobora kuyikoresha kugira ngo ifashe mu mikorere y'umubiri no mu mitekerereze.

Ubu buryo butandukanye bwo gukoresha butuma iba ikintu cyoroshye ku bakora, bigatuma bashobora gukora SKU nyinshi zigamije imiterere y’abaturage batandukanye - kuva ku mirire ya siporo kugeza ku buzima bw’abageze mu zabukuru - bakoresheje ikintu kimwe cy’ingenzi.

Kuki abakora ibicuruzwa bagomba guhitamo umucuruzi wizewe wa ALA?

Kubera ko ALA ishobora kwangirika ku bushyuhe, urumuri na pH, ubwiza bwayo bushobora kwangirika byoroshye hatabayeho kuyikoresha neza. Niyo mpamvu guhitamo umutanga serivisi ufite ikoranabuhanga rigezweho mu gukora no kugenzura ubuziranenge mu buryo bukomeye ari ingenzi cyane.

Abakora ibicuruzwa bagomba gushaka abatanga amakuru y’ibizamini by’abandi (nk’isesengura rya HPLC, GC, n’ibinyabuzima) kugira ngo barebe ko ibicuruzwa bifite isuku n’ubushobozi. Ibi ntibirinda izina ry’ikirango gusa, ahubwo binatuma abantu barushaho gushaka ubwisanzure mu nyongeramusaruro bagura.

Isozwa ry'uburyo bwo kwamamaza

Ifu ya aside ya Alpha Lipoic si ikintu kigezweho gusa - ni igisubizo gishyigikiwe na siyansi ku ngufu, ubuzima bw'imikorere y'umubiri, no kurwanya gusaza. Waba urimo gukora kapsule imwe cyangwa uruvange rugoye kugira ngo ugire akamaro kanini ku buzima, ALA irashobora kugufasha kwigaragaza ku isoko ryuzuye abantu.

Mu gukorana n'umucuruzi wizeye ubuziranenge buhoraho, ibiciro bishimishije, no gutanga ibicuruzwa byizewe, ushobora gutangiza ibicuruzwa bihuye n'ibyo abakiriya bawe bakeneye - kandi ugakomeza kugaruka gushaka ibindi.

Indangamuntu
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Packer, L., Witt, EH, & Tritschler, HJ (1995). Aside ya Alpha-lipoic nk'umuti urwanya indwara ya okisidanti mu binyabuzima. Ubuzima n'Ubuvuzi by'Ubwenge ku buntu, 19(2), 227-250. https://doi.org/10.1016/0891-5849(95)00017-R

Shay, KP, Moreau, RF, Smith, EJ, Smith, AR, & Hagen, TM (2009). Aside Alpha-lipoic nk'inyongera mu mirire: Uburyo bwa molekile n'ubushobozi bwo kuvura. Biochimica et Biophysica Acta (BBA) - Insanganyamatsiko Rusange, 1790 (10), 1149-1160. https://doi.org/10.1016/j.bbagen.2009.07.026

Gomes, MB, & Negrato, CA (2014). Aside Alpha-lipoic nk'ikintu gikoreshwa mu kuvura diyabete n'izindi ndwara zidakira. Diabeteology & Metabolic Syndrome, 6(1), 80. https://doi.org/10.1186/1758-5996-6-80

Rochette, L., Ghibu, S., Richard, C., Zeller, M., Cottin, Y., & Vergely, C. (2013). Imiterere ya antioxydant itaziguye n'itaziguye ya aside alpha-lipoic hamwe n'ubushobozi bwo kuvura. Indyo yuzuye n'ubushakashatsi ku biribwa, 57(1), 114-125. https://doi.org/10.1002/mnfr.201200608

Ziegler, D., Reljanovic, M., Mehnert, H., & Gries, FA (1999). Aside Alpha-lipoic mu kuvura indwara ya diyabete polyneuropathy mu Budage: Ibimenyetso bigezweho bivuye mu bushakashatsi bw'ubuvuzi. Ubushakashatsi ku ndwara za Endocrinology na Diyabete, 107(7), 421-430. https://doi.org/10.1055/s-0029-1212120

Liu, J. (2008). Ingaruka n'uburyo aside alpha-lipoic itungamubiri ya mitochondrial ikora ku kunoza imikorere mibi ya mitochondrial n'ubwonko ifitanye isano n'imyaka: Incamake. Ubushakashatsi ku mitsi, 33(1), 194-203. https://doi.org/10.1007/s11064-007-9479-8