1. Kurwanya Endothelin

Yakuwe mu bimera by’iburayi chamomile, ishobora kurwanya endothelin no kubuza umusaruro wa melanocytes. Ikwirakwizwa rya endothelin mu ruhu ni cyo kintu nyamukuru kiganisha ku gukora pigmentation. Endothelin antagonistes irashobora kubuza endothelin .. tyrosinase no guteza imbere itandukaniro rya melanocytes.

Ubushakashatsi bwerekanye ko antothelin antagonist yakuwe mu binyabuzima byo mu mazi ifite cytotoxicitike nkeya kandi irashobora kubuza itandukaniro rya endothelin kuri melanocytes nigikorwa cya tyrosinase. Indwara hyperpigmentation yuruhu iterwa no kwiyongera -l irashobora kugira ibyifuzo byo gusaba.

2. Resveratrol n'ibiyikomokaho

Resveratrolcyane ibaho mu nzabibu, Polygonum cuspidatum, Veratrum nibindi bimera, kandi ikabuza imikorere ya melanocytes nigikorwa cya tyrosinase muburyo bushingiye ku kwibandaho, bityo bikagabanya synthesis ya melanin. Jeong et al yasanze nayo ifitanye isano na proteyine zijyanye na tyrosinase muri melanogenez.

Jia Lili hamwe nubundi bushakashatsi bwerekanye ko resveratrol yibanze ishobora kuzamura neza ibara ryuruhu, ikagira ingaruka zera, kandi ntigire ingaruka mbi. Resveratrol ifite ibibi byo guhungabana no kubaho bioavailability. Ubushakashatsi bwerekanye ko ibiyikomokaho (ibikomoka kuri pentaalkyl ether n'ibikomoka kuri tetraester) bifite bioavailable nyinshi kandi bishobora kubuza neza synthesis ya melanin. Ifite uburyo bwagutse bwo gukoresha amavuta yo kwisiga.

3. Gukuramo Camellia

Kamellia ni ubwoko bwa Kamellia bwumuryango wa Kamellia. Nakamura n'abandi. yasanze ibimera by'indabyo bya camellia bishobora kubuza umusaruro wa melanin no guteza imbere itandukaniro rya fibroblast. Huang Xiaofeng nubundi bushakashatsi bwanzuye ko ishami ryicyayi cya Dianshan hamwe nibibabi byamababi biruta arbutine mubijyanye no gukwirakwiza selile no kubuza ibikorwa bya tyrosinase, kandi bifite imitungo myiza kuruta arbutine. Nubwoko bushya bwibikoresho byera uruhu kandi bifite uburyo bwinshi bwo gusaba. ibyiringiro.

MelaninSynthaseInhibitor

1. Arbutin

Nibintu byingenzi byangiza tyrosinase, bishobora guhagarika ibikorwa bya tyrosinase, guhagarika synthesis ya dopa na dopaquinone, bityo bikabuza umusaruro wa melanin, kandi birashobora no kugabanya cyane pigmentation iterwa nimirasire ya ultraviolet, ariko ni imikorere idahwitse, hamwe na hamwe amafoto.

Ubushakashatsi bwerekanye ko arbutine ifite ubunini bwa 3% ifite imiterere myiza, cytotoxicitike nkeya, kurakara na allergie, kandi imipaka yo hejuru yibitekerezo byayo ntishobora kurenga 7%. Ubwinshi bwa arbutin buzahindura uruhu rusanzwe. Ibintu bisanzwe bikora, glucopyranoside, bigira ingaruka zikomeye zo kubuza tyrosinase yumuntu kuruta arbutine, kandi igasimbuza arbutine kuko ikora neza kandi ihamye.

2. Gukuramo uruhushya

Ibikoresho byayo bikora cyane cyane likiritine, isoliquiritin na licorice flavonoide. Liquiritin ituma melanin y'uruhu ikwirakwizwa mu gukwirakwiza melanine yegeranijwe, kandi igera ku ngaruka zera; umurimo wingenzi wa licorice flavonoide nuguhagarika ibikorwa bya tyrosinase, DHICA oxydease na dopa pigment intermutase.

Ubushakashatsi bwerekanye ko ubuvuzi bwuruhu rwubuvuzi burimo ibinyomoro na papain bishobora gufasha melasma na hyperpigmentation ya post-inflammatory, hamwe nibisubizo bitari byiza, kandi bifite bimwe .. na .. Ubwinshi bwibicuruzwa byera ni 10% kugeza 40%, ariko ibikubiye mubintu bikora mubisaka ntabwo ari byinshi kandi kweza biragoye kandi bihenze.

3. Gukuramo Chuanxiong

Ubushakashatsi bwerekanye ko ibishishwa bya Chuanxiong bishobora guhagarika neza ibikorwa bya tyrosinase, bikerekana ingaruka zo guhagarika amarushanwa. Amavuta ya Chuanqiong yatejwe imbere binyuze mu mvange ya emulisiferi zitandukanye hamwe n’ibibyimbye bitandukanye, ubushakashatsi ku mikorere yacyo yera no ku mikorere bwerekanye ko 0.5% ~ 1.0% amavuta ya Chuanqiong afite ibiranga ituze ryiza, imikorere myiza n'ingaruka nziza zo kwera.

4. Rhodiola Rosea

Salidroside na flavonoide nibintu byingenzi bikora, kandi salidroside irashobora kwangiza lipide hamwe na selile hamwe nimirasire ya ultraviolet. Ibikuramo birashobora kubuza synthesis ya melanin nigikorwa cya tyrosinase, kandi nikintu cyiza cyo kwera uruhu. Ubushakashatsi bwerekanye ko 1% na 5% by’ibiti bya Rhodiola rosea bitigeze bitera ingaruka mbi mu mubiri w’umuntu, kandi ni ibintu byo kwisiga bikora neza kandi bifite ibyiringiro byinshi mu kwisiga.

5. Aloin

Nibimera bifite uburemere buke glycoproteine ​​yakuwe muri aloe vera. Irabuza cyane cyane gushiraho dopaquinone mukurwanya guhatanira ikibanza cya okiside ya dopa, kandi ikagera kubuza guhatanwa no guhatanira kubuza ion umuringa kurubuga rwa hydroxylase. Igikorwa cya hydroxylase ya tyrosine. Byongeye kandi, aloin irashobora kandi kugabanya umwijima wuruhu iterwa nimirasire ya ultraviolet, kandi ikagira ingaruka nziza zo gusana kuruhu nyuma yizuba. Aloin ni hydrophilique kandi itari cytotoxic. Kuvanga aloin na arbutin birashobora kunoza ingaruka zo kwera.

6. Tera Polifenol

Bibaho cyane cyane mubishishwa, imizi, amababi n'imbuto byibimera, kandi ingaruka zayo zera zifitanye isano cyane no kwinjiza imirasire ya ultraviolet, kurandura antioxydeant ya radicals yubuntu, no kubuza ibikorwa bya tyrosinase na peroxidase. Acide Ellagic ni polifenol isanzwe ikurwa mu gishishwa cy'amakomamanga, ibishishwa n'imbuto n'imboga zitandukanye. Irashobora kubuza ikwirakwizwa rya melanocytes, ikabuza ibikorwa bya melanocyte tyrosinase, kugabanya synthesis ya melanin, imirasire ya Ultraviolet igira ingaruka zikomeye zo gukurura izuba, ishobora kugira uruhare mukurinda izuba cyangwa gusibanganya radicals yubusa ikoresheje imirasire ya ultraviolet. Ibimera bya polifenol ni ubwoko bwingirakamaro, bufite ibyerekezo byinshi byiterambere no gukoresha amavuta yo kwisiga.

Ibisobanuro birambuye:
Shaanxi Ruiwo Phytochem Co, Ltd.
Umuyobozi mu mahanga: Jason
Mob: 0086-18629669868
Imeri:jason@ruiwophytochem.com
Whatsapp: 008618629669868