Ishyirwa mu bikorwa rya Citrus Aurantium

Aurantium y'ibinure, ikimera kiri mu muryango wa rutaceae, gikwirakwizwa cyane mu Bushinwa. Citrus aurantium ni izina gakondo ry'igishinwa ry'indimu. Mu buvuzi gakondo bw'Abashinwa, citrus aurantium ni ikimera gakondo gakondo gikoreshwa cyane cyane mu kongera ubushake bwo kurya no kugenga qi (ingufu). Mu Butaliyani, citrus aurantium nayo yabaye umuti gakondo kuva mu kinyejana cya 16, ikoreshwa mu kuvura umuriro nka malariya ndetse no nk'umuti urwanya udukoko. Ubushakashatsi buherutse bwerekanye ko citrus aurantium ishobora gusimbura ephedra mu kuvura umubyibuho ukabije nta ngaruka mbi z'umutima n'imitsi.

Ibigize ikinyabutabire cy’umunyu ni hesperidin, neohesperidin, nobiletin, auranetin, aurantiamarin, nuringin, synephrine, limonin.

Ikintu gikora

hesperidin, neohesperidin, nobiletin, D-limonene, auranetin, aurantiamarin, citrin, synephrine, limonin

Imitungo ifatika

Gushonga kw'amakristali, aho gushonga 184-1850C, gushonga kw'amakristali karubone 151-152, byoroshye gushonga mu mazi. Bitartrate, aho gushonga 188-189, ishonga mu mazi, bigoranye gushonga muri ethanoli, hafi ya idashonga muri chloroform, ether. Hydrochloride, kristu idafite ibara (ethanol-ethyl ether), aho gushonga 166-167. Gushonga kw'amakristali biroroshye kubaho mu gutandukanya aside ikomeye na resins z'ihindagurika rya iyoni.

Ingaruka z'imiti
1. Ingaruka ku mura: Fructus Aurantii na Fructus Aurantii Fructus Decoction iturutse ahantu hatatu hatandukanye (Sichuan, Jiangxi, na Hunan) yagaragaje ingaruka zo kubuza nyababyeyi mu buryo bwa vitro ku mbeba (zitwite n’izidatwite); nyababyeyi y’urukwavu yari yishimye haba mu buryo bwa vitro no mu buryo bwa vitro (zitwite kandi zitatwite). Fistula y’urukwavu na yo yagaragaje ko ituma nyababyeyi ikomera, yongera imbaraga, ndetse ikanatuma nyababyeyi ikomera. Fructus Aurantii tincture na Fructus Aurantii fluid extract nabyo bishobora gukurura nyababyeyi y’urukwavu (mu buryo bwa vitro no mu buryo bwa vitro). nyababyeyi y’imbeba (mu buryo bwa vitro) byarahagaritswe. Alkaloid yakuwe muri Fructus Aurantii na Lycium orange na yo yagize ingaruka zimwe na zimwe ku mura y’urukwavu mu buryo bwa vitro, cyane cyane ku mitsi y’urukwavu yakuruwe na pituitrin. Igice cya alkaloid cyakuweho cyagize ingaruka zo kuruhuka nyababyeyi y’urukwavu mu buryo bwa vitro, kandi ingaruka zo kuruhuka nyababyeyi zagaragaye cyane nyuma yo gushyuha cyane. Cirantin, yakuwe muri Fructus Aurantii Fructus Peel, ibuza imikorere ya hyaluronate hafi y'intanga ngore, ibi bikaba bishobora kuba bifitanye isano n'ingaruka zayo zo kuboneza urubyaro (kubuza imisemburo).

2. Ingaruka ku mara: Fructus Aurantii na Fructus Aurantii bo mu duce dutatu dutandukanye babujije amara mu mbeba n'inkwavu; Inyinshi mu miyoboro y'amara mu nkwavu zarabujijwe, ariko nkeya nta mpinduka zagize. Fructus Aurantii n'amazi yayo byabujije imiyoboro y'amara y'imbeba (in vitro) n'inkwavu (in vitro). Kwiyongera cyane (1:1000) byabujije amara mato y'inkwavu n'ingurube zo mu bwoko bwa Guinea kandi bibuza ingaruka za acetylcholine na histamine. Kwiyongera guke (1:10 000), nyuma y'igihe gito cyo kugabanya, bishobora kugaragaza ingaruka zo gushyuha, ubwinshi bw'amara bwiyongera, kandi inshuro nyinshi zikihuta. Mu mbwa zatewe ikinya, kubaho kw'amara kwari gukumirwa birumvikana hakoreshejwe imiti igabanya ubukana. Ariko ku mbwa zifite gastroenterostomy, ifite ingaruka zimwe na zimwe zo gushyuha, zishobora gutuma igogora ry'igifu n'imitsi yo kubyimba bikomera.

3. Ingaruka ku mutima no mu mitsi y'amaraso: ingano nto y'umuvuduko n'ubwinshi bw'ingufu ku mutima w'ikinyobwa mu buryo bwa vitro. Umutobe w'amazi wa Fructus Aurantii na Fructus Aurantii, umutobe w'amazi wa Fructus Aurantii, n'umutobe w'amazi ni bimwe. Umutobe w'amazi wa Fructus Aurantii cyangwa umutobe w'inzoga uterwa mu mitsi ushobora gutuma umuvuduko w'amaraso wiyongera cyane. Fructus Aurantii na Fructus Aurantii Fructus ikomoka mu duce dutatu dutandukanye byagaragaye ko igira ingaruka zo kugabanya imitsi y'amaraso bitewe no kunyura kw'imitsi y'ikinyobwa mu mubiri wose. Mu mbwa zahawe ikinya, habayeho ingaruka zikomeye kandi zihuse z'umuvuduko w'amaraso ukabije. Nta gucika intege k'ubuhumekero cyangwa kugabanuka k'amaraso kwatewe na epinephrine, kandi nta kwiyongera k'umutima kwagaragaye.

Uburyo bwo kongera umuvuduko bufitanye isano n'ibintu bikurikira:

3.1. Gushyuha kwa α receptors, bigatera vasoconstriction muri zimwe mu ngingo z'umubiri (phenylzoline ishobora gusubiza inyuma ukwiyongera k'umuvuduko w'amaraso mu mubiri ikaba irwanya umuvuduko ukabije w'amaraso).

3.2. Kongera imbaraga mu mitsi no kongera imbaraga z'umutima (gusohora umutima w'ingurube y'ingurube yihariye no gutegura umutima n'imitsi y'umutima). Nyuma yo gufata reserpine, ingaruka zo kongera umuvuduko wa Fructus aurantii aurantii zari zikomeye cyane. Yongereye cyane imitsi y'umutima (289.4% byiyongereye imitsi y'umutima igenda hifashishijwe icyuma gipima ubwinshi bw'amaraso) kandi yongereye amaraso yo mu bwonko n'impyiko ku kigero cya 86.4% na 64.5% ugereranije, byari bitandukanye cyane na norepinephrine. Habayeho kugabanuka kw'imitsi y'amaraso yo mu gitsina no kwiyongera gato ariko ku bushobozi buke bwo gukoresha ogisijeni mu mutima, bitahuriranye n'ubwiyongere bunini bw'imitsi y'umutima. Mu bizamini bya ECG ku mbwa n'ingurube y'ingurube, arrhythmia (ventricular tachycardia cyangwa atrioventricular block) iterwa n'umuvuduko munini wa aurantii aurantii ntabwo byari bikomeye. Hashingiwe ku miterere yavuzwe haruguru, byavuzwe ko ivura indwara z'umutima. Alkaloids zakuwe muri Fructus Aurantii na Lycium orange nazo zishobora kongera by'agateganyo imbaraga z'imitsi yoroshye y'amaraso, cyane cyane iyo zivuwe na pituitrin.

4. Kurwanya indwara yo kugabanya imitsi: Isuzuma ryakozwe muri vitro rya 0.1g/ml rya Fructus Aurantii aqua decoction ryagaragaje ingaruka zigaragara zo kurwanya indwara yo kugabanya imitsi.

5. Indwara yo kurwanya allergie: 100mg/kg iterwa ry’amazi ya Fructus Aurantii Aurantii ishobora gukumira allergie y’uruhu idakora (PCA) mu mbeba, naho 50μg/ml ishobora kubuza irekurwa rya histamine mu turemangingo tw’inda tw’imbeba.

6. Izindi ngaruka: Mycin y'ibimera bya citrus ishobora kugabanya ingano ya cholestatin mu maraso no mu mwijima w'imbeba zigaburirwa indyo irimo cholesterol. Inzoga ya Fructus Aurantii yagize ingaruka zo gukumira mycobacterium tuberculosis H37Rv muri vitro, kandi ingano yayo yo gukumira yari 1:1000. Umutobe wayo w'amazi ntacyo wagize ku ifu ya Guinea Pig Bronchus. Byatangajwe ko umutobe w'imbuto za citrus wongera umuvuduko wo guhisha umusemburo kandi ntugabanya imikorere yawo nyuma yo kubira, bityo ntabwo ari igice cya enzyme. Ikoreshwa ry'ingenzi ry'umutobe w'icunga mu buvuzi ni uko ukungahaye kuri vitamine C kandi urimo vitamine A na B nyinshi. Igishishwa ntikirimo vitamine C ahubwo gikungahaye kuri vitamine A. Kiraryoha kandi gishobora gukomeza igifu. Abana nko gufata igishishwa kinini bashobora gutera uburozi (ububabare bwo mu nda, kuribwa mu nda).

Ireferensi: http://www.a-hospital.com

KuriIkinyabutabire cya Citrus Aurantium, turagusaba kutwandikira. Turagutegereje hano igihe icyo ari cyo cyose!!!