Intangiriro ya Citrus Aurantium

Citrus Aurantium, igihingwa cyumuryango wa rutaceae, gikwirakwizwa cyane mubushinwa. Citrus aurantium nizina gakondo ryigishinwa kuri lime. Mu buvuzi gakondo bw'Abashinwa, citrus aurantium ni icyatsi gakondo gikoreshwa cyane mu kongera ubushake bwo kurya no kugenzura qi (ingufu). Mu Butaliyani, citrus aurantium nayo yabaye umuti gakondo kuva mu kinyejana cya 16, ikoreshwa mu kuvura umuriro nka malariya ndetse no mu miti igabanya ubukana. Ubushakashatsi buherutse gukorwa bwerekanye ko citrus aurantium ishobora gusimbuza ephedra mu kuvura umubyibuho ukabije nta ngaruka mbi z'umutima n'imitsi.

Ikintu cyiza cya citrus aurantium ni hesperidin, neohesperidin, nobiletin, auranetin, aurantiamarin, nuringin, synephrine, limonine.

Ibikoresho bifatika

hesperidin, neohesperidin, nobiletin, D-limonene, auranetin, aurantiamarin, citrin, synephrine, limonin

Umutungo wumubiri

Crystallisation, gushonga 184-1850C, karubone ya karubone 151-152, byoroshye gushonga mumazi. Bitartrate, gushonga ingingo 188-189, gushonga mumazi, bigoye gushonga muri Ethanol, hafi yo kudashonga muri chloroform, ether. Hydrochloride, kirisiti itagira ibara (Ethanol-Ethyl ether), gushonga 166-167. Ivanguramoko ryoroshe kugaragara mugutandukanya chromatografiya ya acide ikomeye hamwe na base yo guhana ion.

Ingaruka ya farumasi
. Inkondo y'inkwavu yishimye haba muri vivo ndetse no muri vitro (utwite kandi udatwite). Fistula y'inkwavu na yo yerekanye ko itera inkondo y'umura gukomera, kongera umuvuduko, ndetse no kwikuramo tetanic. Tructure ya Fructus Aurantii hamwe na Fructus Aurantii ikuramo amazi nayo irashobora gushimisha nyababyeyi y'inkwavu (muri vivo no muri vitro). Inda y'imbeba (muri vitro) yarabujijwe. Ikintu cya alkaloide gitandukanijwe na Fructus Aurantii na Lycium orange nacyo cyagize ingaruka zimwe na zimwe kuri nyababyeyi y'inkwavu muri vitro, cyane cyane ku mitsi ya nyababyeyi ishimishijwe na pituitrin. Igice cya alkaloide yakuweho cyagize ingaruka zo kuruhuka kuri nyababyeyi yinkwavu muri vitro, kandi ingaruka zo kuruhuka kwa nyababyeyi zagaragaye cyane nyuma yo kwishima hypophysial. Cirantin, yitandukanije na Fructus Aurantii Peructus Peel, ibuza ibikorwa bya hyaluronate hafi yintanga ngore, bishobora kuba bifitanye isano n'ingaruka zo kuboneza urubyaro (kwirinda gusama).

2. Ingaruka ku mara: Fructus Aurantii na Fructus Aurantii kuva ahantu hatatu hatandukanye byabujije amara imbeba ninkwavu; Imiyoboro myinshi yo munda mu nkwavu yarabujijwe, ariko bake ntibahindutse. Fructus Aurantii hamwe nibisohoka byamazi yabujije imiyoboro yo munda yimbeba (muri vitro) ninkwavu (muri vitro). Kwibanda cyane (1: 1000) byabujije amara mato yinkwavu n’ingurube byitaruye kandi birinda ingaruka za acetylcholine na histamine. Kwibanda hasi (1:10 000), nyuma yigihe gito cyo kubuzwa, birashobora kwerekana ingaruka zishimishije, amplitude yiyongereye, kandi inshuro yihuta. Mu mbwa zatewe aneste, kuba amara byarabujijwe bigaragara ko ari uburiganya. Ariko ku mbwa zifite gastroenterostomy, zifite ingaruka zishimishije, zishobora gutuma gastrointestinal igenda hamwe nigitekerezo cyo kwikuramo imbaraga.

3. Ingaruka kumutima nimiyoboro yamaraso: ubwinshi bwibyishimo hamwe nubwinshi bwo kubuza kumutima wigituba muri vitro. Fructus Aurantii na Fructus Aurantii Aurantii amazi yo mu mazi, tincure ya Fructus Aurantii, hamwe nibisukari byamazi ni bimwe. Fructus Aurantii decoction cyangwa ibinyobwa bisindisha byatewe mumitsi bishobora kuvamo imbaraga zikomeye. Fructus Aurantii na Fructus Aurantii Fructus kuva ahantu hatatu hatandukanye byagaragaye ko ifite ingaruka zoroheje za vasoconstriction ziterwa numubiri wose wamaraso yimitsi. Mu mbwa zatewe aneste, habaye ingaruka zikomeye kandi zihuse. Nta kwiheba k'ubuhumekero cyangwa hypotension byatewe na epinephrine, kandi nta kwiyongera kugaragara k'umutima.

Uburyo bwo kongera ingufu bujyanye nibintu bikurikira:

3.1. Ibyishimo bya α reseptors, bitera vasoconstriction mu ngingo zimwe na zimwe (fenylzoline irashobora guhindura umuvuduko ukabije muburyo bwa antivypertensive reaction).

3.2. Kongera imbaraga za myocardial no kongera umutima wumutima (guinea yingurube yingurube yumutima no gutegura umutima). Nyuma ya reserpine, ingaruka zo kongera ingufu za Fructus aurantii aurantii zari zikomeye cyane. Yiyongereye ku buryo bugaragara imiyoboro y'amaraso (289.4% yiyongereyeho imiyoboro y'amaraso na bubble flowmeter) kandi yongera ubwonko n'amaraso y'impyiko ku kigero cya 86.4% na 64.5% ugereranije, byari bitandukanye cyane na norepinephrine. Habayeho kugabanuka kwamaraso yumugore no kwiyongera gake ariko bidafite akamaro mukunywa ogisijeni ya myocardial, bitajyanye no kwiyongera gukabije kwimitsi. Mu bizamini bya ECG mu mbwa n'ingurube, arththmia (tachycardia ya ventricular cyangwa block atrioventricular block) yatewe numubare munini wa aurantii aurantii ntabwo yari ikomeye. Ukurikije ibimenyetso byavuzwe haruguru, hasabwe kuvura indwara yumutima. Alkaloide yitandukanije na Fructus Aurantii na Lycium orange irashobora kandi kongera by'agateganyo imitsi y'imitsi yoroshye y'amaraso, cyane cyane iyo ivuwe na pituitrine.

4.

5.

6. Izindi ngaruka: Citrus yibihingwa mycin irashobora kugabanya ibirimo cholestatine muri serumu numwijima wimbeba zagaburiwe nimirire irimo cholesterol. Ibinyobwa bisindisha bya Fructus Aurantii byagize ingaruka mbi kuri mycobacterium tuberculose H37Rv muri vitro, kandi kwibanda kwayo kwari 1: 1000. Amazi yo mu mazi yayo nta ngaruka yagize kuri guinea ingurube bronchus. Byavuzwe ko umutobe wimbuto za citrus wongera umuvuduko wa fermentation yumusemburo kandi ntugabanye ibikorwa byawo nyuma yo guteka, ntabwo rero ari ibintu bitera imisemburo. Uburyo bukoreshwa mubuvuzi bwumutobe wamacunga nuko bukungahaye kuri vitamine C kandi burimo vitamine A na B. Umubare munini wa vitamine A ariko ukungahaye kuri vitamine A. Iraryoshye kandi irashobora gukomera igifu. Abana nko gufata ibishishwa byinshi birashobora gutera uburozi (kubabara munda, kubabara).

Reba ： http: //www.a-ibitaro.com

KuriCitrus Aurantium, nyamuneka twandikire. Turagutegereje hano umwanya uwariwo wose !!!