Uruhu n'imbuto z'inzabibu n'imbuto zirimo resveratrol, bigatuma divayi itukura ikungahaye kuri uru ruganda. Ubushakashatsi bwerekana ko bufite akamaro kanini mubuzima, ariko ugomba kumenya byinshi kubijyanye ninyongera ukeneye gufata.
Niba warigeze wumva ko vino itukura ifasha kugabanya cholesterol, noneho ushobora kuba warigeze wumva resveratrol, uruganda rwibimera ruzwi cyane muri vino itukura.
Ariko usibye kuba igice cyingirakamaro cya vino itukura nibindi biribwa, resveratrol nayo ifite ubuzima bwiza.
Mubyukuri, inyongera ya resveratrol ifitanye isano nibyiza byinshi byubuzima, harimo kurinda imikorere yubwonko no kugabanya umuvuduko wamaraso (1, 2, 3, 4).
Iyi ngingo isobanura ibyo ukeneye kumenya kuri resveratrol, harimo nibyiza birindwi byingenzi byubuzima.
Resveratrol ni uruganda rwibimera rukora nka antioxydeant. Amasoko y'ingenzi y'ibiribwa arimo vino itukura, inzabibu, imbuto zimwe, n'ibishyimbo (5, 6).
Uru ruganda rukunda kwibanda ku mpu n'imbuto z'inzabibu n'imbuto. Ibi bice byinzabibu bigira uruhare muguhindura divayi itukura bityo bikaba bifite resveratrol cyane (5, 7).
Nyamara, ubushakashatsi bwinshi bwa resveratrol bwakorewe mu nyamaswa no mu tubari twipimishije dukoresheje umubare munini w’uru ruganda (5, 8).
Mu bushakashatsi buke ku bantu, benshi bibanze ku buryo bwiyongereye bw’imvange, buboneka mu bwitonzi burenze ubw'ibikomoka ku biryo (5).
Resveratrol ni antioxydeant iboneka muri vino itukura, imbuto n'imbuto. Ubushakashatsi bwinshi bwabantu bwakoresheje inyongera zirimo urugero rwa resveratrol.
Bitewe na antioxydeant, resveratrol irashobora kuba inyongera itanga ikizere cyo kugabanya umuvuduko wamaraso (9).
Isuzuma ryo mu 2015 ryanzuye ko dosiye nyinshi zishobora gufasha kugabanya imihangayiko ku rukuta rw'imitsi iyo umutima uteye (3).
Uyu muvuduko witwa umuvuduko wamaraso wa systolique kandi ugaragara nkumubare munini mugusoma umuvuduko wamaraso.
Umuvuduko wamaraso wa systolique wiyongera uko imyaka igenda ishira bitewe na aterosklerose. Iyo ari hejuru, ni ibintu bishobora gutera indwara z'umutima.
Resveratrol irashobora kugera ku ngaruka zo kugabanya umuvuduko wamaraso ifasha kubyara aside nitide nyinshi, itera imiyoboro yamaraso kuruhuka (10, 11).
Icyakora, abanditsi b'ubushakashatsi bavuze ko hakenewe ubushakashatsi bwinshi kugira ngo hatangwe ibyifuzo byihariye ku gipimo cyiza cya resveratrol ku ngaruka nini ku muvuduko w'amaraso.
Ubushakashatsi bwinshi bw’inyamaswa bwerekanye ko inyongera ya resveratrol ishobora guhindura lipide yamaraso muburyo bwiza (12, 13).
Mu bushakashatsi bwakozwe mu mwaka wa 2016, imbeba zagaburiwe indyo yuzuye proteyine hamwe n’amavuta ya polyunzure yuzuye hiyongeraho resveratrol.
Abashakashatsi basanze impuzandengo ya cholesterol yuzuye hamwe nuburemere bwumubiri wimbeba byagabanutse, mugihe urwego rwa cholesterol ya “nziza” HDL yiyongereye (13).
Resveratrol isa nkaho igira ingaruka kuri cholesterol mukugabanya ibikorwa byimisemburo igenzura umusaruro wa cholesterol (13).
Nka antioxydeant, igabanya kandi okiside ya “cholesterol” LDL “mbi”. Oxidation ya LDL itera gukora plaque murukuta rwa arterial (9, 14).
Nyuma y'amezi atandatu yo kwivuza, abitabiriye gufata imiti yinzabibu cyangwa insimburangingo zidafite intungamubiri zagabanutseho 4.5% muri LDL no kugabanuka kwa 20% LDL (15).
Inyongera ya Resveratrol irashobora kuzamura urugero rwamaraso mu nyamaswa. Kuba antioxydants, bigabanya kandi okiside ya cholesterol ya LDL.
Ubushobozi bwikomatanya bwo kongera igihe cyibinyabuzima bitandukanye byahindutse igice kinini cyubushakashatsi (16).
Hariho ibimenyetso byerekana ko resveratrol ikora genes zimwe na zimwe, bityo ikarinda indwara zo gusaza (17).
Ibi bikora muburyo busa no kubuza calorie, byagaragaje ibisubizo bitanga umusaruro mukwongera igihe cyo kubaho uhindura uburyo gen zigaragazwa (18, 19).
Isubiramo ry’ubushakashatsi bwasuzumye iyi sano ryerekanye ko resveratrol yongereye igihe cyo kubaho muri 60% y’ibinyabuzima byize, ariko ingaruka zagaragaye cyane mu binyabuzima bidafitanye isano rya bugufi n’abantu, nk'inyo n'amafi (20).
Ubushakashatsi bw’inyamaswa bwerekanye ko inyongera ya resveratrol ishobora kongera igihe cyo kubaho. Ariko, ntibisobanutse niba bizagira ingaruka nkizo mubantu.
Ubushakashatsi bwinshi bwerekanye ko kunywa vino itukura bishobora gufasha gutinda kugabanuka kwubwenge (21, 22, 23, 24).
Bigaragara ko bibangamira ibice bya poroteyine bita amyloide beta, bigira uruhare runini mu gushiraho icyapa kiranga indwara ya Alzheimer (21, 25).
Nubwo ubu bushakashatsi bushimishije, abahanga baracyafite ibibazo bijyanye nubushobozi bwumubiri bwo gukoresha resveratrol yiyongera, bikagabanya guhita ikoreshwa nkinyongera ikingira ubwonko (1, 2).
Resveratrol ni antioxydants ikomeye kandi irwanya inflammatory ishobora kurinda ingirabuzimafatizo ubwonko kwangirika.
Izi nyungu zirimo kunoza insuline no kwirinda indwara ya diyabete (26,27,28,29).
Igisobanuro kimwe cyukuntu resveratrol ikora nuko ishobora kubuza enzyme guhindura glucose muri sorbitol, inzoga yisukari.
Iyo sorbitol nyinshi yegeranije mumibiri yabantu barwaye diyabete, irashobora gutera okiside yangiza selile (30, 31).
Resveratrol irashobora no kugirira akamaro abarwayi ba diyabete kurusha abantu badafite diyabete. Mu bushakashatsi bumwe bw’inyamaswa, vino itukura na resveratrol byagaragaye ko ari antioxydants ikomeye mu mbeba za diyabete kuruta mu mbeba zitari diyabete (32).
Abashakashatsi bavuga ko uru ruganda rushobora gukoreshwa mu kuvura diyabete n'ingaruka zayo mu gihe kiri imbere, ariko hakenewe ubushakashatsi bwinshi.
Resveratrol ifasha imbeba kunoza insuline no kurwanya indwara ya diyabete. Mu bihe biri imbere, abarwayi ba diyabete barashobora no kungukirwa no kuvura resveratrol.
Inyongeramusaruro zirimo kwigwa nkuburyo bwo kuvura no kwirinda ububabare bufatanye. Iyo ifashwe nk'inyongera, resveratrol irashobora gufasha kurinda karitsiye kumeneka (33, 34).
Ubushakashatsi bumwe bwinjije resveratrol mu mavi y’inkwavu ya rubagimpande maze isanga izo nkwavu zangiritse cyane (34).
Ubundi bushakashatsi bwa tube-tube hamwe nubushakashatsi bwinyamaswa bwerekanye ubwo bushobozi bwo kugabanya umuriro no kwirinda kwangirika (33, 35, 36, 37).
Resveratrol yakozweho ubushakashatsi ku bushobozi ifite bwo kwirinda no kuvura kanseri, cyane cyane mu tubari twipimishije. Ariko, ibisubizo byaravanze (30, 38, 39).
Byerekanwe kurwanya kanseri zitandukanye za kanseri mu bushakashatsi bw’inyamaswa n’ibizamini, harimo igifu, umura, uruhu, amabere, na kanseri ya prostate (40, 41, 42, 43, 44).
Nyamara, kubera ko ubushakashatsi kugeza ubu bwakorewe mu tubari no mu nyamaswa, hakenewe ubushakashatsi bwinshi kugira ngo twumve niba n’uburyo iyi nteruro ishobora gukoreshwa mu kuvura kanseri mu bantu.
Ubushakashatsi ukoresheje inyongera ya resveratrol bwasanze nta ngaruka zikomeye. Bigaragara ko bihanganirwa neza nabantu bafite ubuzima bwiza (47).
Ariko, twakagombye kumenya ko muri iki gihe habuze ibyifuzo byuzuye bijyanye n’amafaranga resveratrol umuntu agomba gufata kugirango abone inyungu zubuzima.
Hariho kandi umuburo, cyane cyane kubyerekeranye nuburyo resveratrol ikorana nindi miti.
Kubera ko ibipimo byinshi byagaragaye ko birinda ko amaraso atembera mu tubari twipimishije, birashobora kongera kuva amaraso cyangwa gukomeretsa iyo bifashwe na anticagulants nka heparin cyangwa warfarin, cyangwa imiti imwe n'imwe y'ububabare (48, 49).
Resveratrol nayo ihagarika imisemburo ifasha gukuramo ibice bimwe na bimwe mumubiri. Ibi bivuze ko imiti imwe n'imwe ishobora kugera kurwego rutekanye. Muri byo harimo imiti igabanya umuvuduko w'amaraso, imiti igabanya ubukana, hamwe na immunosuppressants (50).
Niba ubu urimo gufata imiti, urashobora kuvugana na muganga mbere yo gufata resveratrol.