Inyongera yitwa 5-hydroxytryptophan (5-HTP) cyangwa osetriptan ifatwa nkubundi buryo bwo kuvura umutwe hamwe na migraine. Umubiri uhindura iyi ngingo muri serotonine (5-HT), izwi kandi nka serotonine, neurotransmitter igenga imyumvire nububabare.
Urwego rwa serotonine nkeya rukunze kugaragara ku bantu bafite ikibazo cyo kwiheba, ariko ababana na migraine hamwe n’abarwaye umutwe udakira na bo bashobora guhura na serotonine nkeya mu gihe no hagati y’ibitero. Ntibyumvikana impamvu migraine na serotonine bifitanye isano. Igitekerezo gikunzwe cyane nuko kubura serotonine bituma abantu batumva ububabare.
Kubera iyo sano, uburyo bwinshi bwo kongera ibikorwa bya serotonine mubwonko bukoreshwa muburyo bwo kwirinda migraine no kuvura ibitero bikaze.
5-HTP ni aside amine ikorwa numubiri kuva aside amine ya L-tryptophan kandi igomba kuboneka mubiryo. L-tryptophan iboneka mu biribwa nk'imbuto, soya, turukiya na foromaje. Enzymes mubisanzwe ihindura L-tryptophan muri 5-HTP, hanyuma igahindura 5-HTP muri 5-HT.
5-HTP inyongera ikozwe mu gihingwa cy’imiti cyo muri Afurika y’iburengerazuba Griffonia simplicifolia. Iyi nyongera yakoreshejwe mu kuvura indwara yo kwiheba, fibromyalgia, syndrome de fatigue idakira, no kugabanya ibiro, ariko nta bimenyetso bifatika byerekana inyungu zayo.
Iyo usuzumye 5-HTP cyangwa inyongeramusaruro isanzwe, ni ngombwa kumva ko ibyo bicuruzwa ari imiti. Niba ubifata kuko bifite imbaraga zihagije kugirango bigire ingaruka nziza kubuzima bwawe, uzirikane ko bishobora no gukomera bihagije kugirango bigire ingaruka mbi.
Ntibyumvikana niba inyongera 5-HTP ari ingirakamaro kuri migraine cyangwa ubundi bwoko bwumutwe. Muri rusange, ubushakashatsi bugarukira; ubushakashatsi bumwe bwerekana ko bufasha, mugihe ibindi byerekana ko nta ngaruka.
Ubushakashatsi bwa Migraine bwakoresheje dosiye ya 5-HTP iri hagati ya 25 na 200 mg kumunsi kubantu bakuru. Kugeza ubu nta dosiye isobanutse cyangwa isabwa kuri iyi nyongera, ariko birakwiye ko tumenya ko dosiye nyinshi zifitanye isano n'ingaruka no guhuza ibiyobyabwenge.
5-HTP irashobora gukorana n'imiti imwe n'imwe, harimo karbidopa, ikoreshwa mu kuvura indwara ya Parkinson. Irashobora kandi gukorana na triptans, SSRIs, na monoamine oxydease inhibitor (MAOIs, ikindi cyiciro cya antidepressants).
Tryptophan hamwe ninyongera 5-HTP irashobora kwanduzwa nibintu bisanzwe 4,5-tryptophanione, neurotoxine izwi kandi nka Peak X. Ingaruka ziterwa na Peak X zirashobora gutera ububabare bwimitsi, kubabara, no kugira umuriro. Ingaruka z'igihe kirekire zishobora kuba zirimo imitsi no kwangirika kw'imitsi.
Kubera ko iyi miti ikomoka kumiti kandi ntabwo ari umwanda cyangwa umwanda, irashobora kuboneka mubyongeweho nubwo byateguwe mugihe cyisuku.
Ni ngombwa kuganira ku gufata ibyongeweho na muganga wawe cyangwa umufarumasiye kugirango umenye neza ko ari umutekano kuri wewe kandi ko utazakorana nindi miti yawe.
Wibuke ko inyongeramusaruro nimboga zibyatsi bitigeze bigira ubushakashatsi bukomeye nigeragezwa nkimiti irenga imiti kandi yandikiwe imiti, bivuze ko ubushakashatsi bushigikira imikorere yabyo n'umutekano ari bike cyangwa bituzuye.
Inyongera nubuvuzi karemano burashobora kuba byiza, cyane cyane niba bidafite ingaruka. Mubyukuri, imiti karemano yagaragaye ko ifite akamaro kuburwayi bwinshi. Hariho ibimenyetso byerekana ko inyongera ya magnesium ishobora kugabanya inshuro nuburemere bwibitero bya migraine. Ariko, ntibisobanutse niba 5-HTP ifitiye akamaro migraine.
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Teri Robert Teri Robert numwanditsi, umwarimu wihangana, nuwunganira abarwayi kabuhariwe muri migraine no kubabara umutwe.