Acide ya Arachidonic (ARA), acide docosahexaenoic (DHA) na aside eicosapentaenoic (EPA) ni urunigi rurerure rwa polyunsaturated fatty acide (LCPUFA). Carotenoide, harimo lutein na zeaxanthin (LZ), iboneka cyane mu mboga rwatsi.
ARA na DHA ni byinshi mu bwonko kandi ni ibintu by'ingenzi bigize fosifolipide. Ubushakashatsi bwerekanye ko kuzuza ibipimo byinshi bya DHA na EPA bishobora kunoza imikorere yibuka kubantu bakuze.
Byongeye kandi, LZ, antioxydants igizwe nubwonko, byavuzwe ko igira ingaruka zo kurinda ingirabuzimafatizo, bityo bikagira ingaruka kumikorere yubwenge. Nyamara, imikorere ya lutein na zeaxanthin kumikorere yibuka ntisobanutse kubera ibisubizo bivuguruzanya bivuye mubushakashatsi bwakozwe mbere.
Hashingiwe ku kuba ARA, DHA, EPA, L na Z (LCPUFA + LZ) biboneka mu bwonko, ndetse na raporo zimwe na zimwe zerekana imikorere myiza yo kwibuka, abanditsi b'ubu bushakashatsi bavuze ko guhuza ibyo bintu bishobora gutera imbere kwibuka. imikorere mu bwonko. abantu bakuze bafite ubuzima bwiza.
Abashakashatsi b'Abayapani bakoze ibyumweru 24, batabishaka, bahumye-buhumyi, bagenzurwa na platbo, bigereranya itsinda ry’ingaruka za LCPUFA + LH ku mikorere yo kwibuka ku bageze mu za bukuru b'Abayapani bafite ibibazo byo kwibuka ariko nta guta umutwe.
Basanze nta tandukaniro rikomeye riri hagati yitsinda. Nyamara, mu isesengura ryakozwe ryitsinda ryabitabiriye hamwe no kugabanuka kwubwenge, byagaragaye ko hari iterambere ryinshi.
Raporo isoza igira iti: “Ubu bushakashatsi bwerekana ku nshuro ya mbere ko guhuza LCPUFA na LZ bishobora guteza imbere imikorere yo kwibuka ku bantu bakuze b'Abayapani bakuze bafite ubumuga bwo kutamenya ariko nta guta umutwe.” 'inyandiko ad1 ′); });
Abitabiriye 120 baturutse muri Tokiyo no mu karere kegeranye batoranijwe mu matsinda atatu: (1) itsinda rya placebo ryakira umwanya wabo nk'inyongera y'ibiryo; (2) itsinda rya placebo ryakira umwanya winyongera yimirire; (2)). Itsinda LCPUFA + X ryakiriye inyongera yimirire igizwe na LCPUFA (irimo mg 120 ARA, 300 mg DHA na 100 mg EPA kumunsi) hamwe na Compound X (iterekanwa nkuko iyi nteruro itari ingingo yubu bushakashatsi)) (3) LCPUFA Itsinda rya LH ryakira inyongera yimirire igizwe na LCPUFA (120mg ARA, 300mg DHA na 100mg EPA kumunsi) ifatanije na LH (10mg lutein na 2mg zeaxanthin kumunsi).
Ibiryo byubushakashatsi nibikoresho byatanzwe muri ubu bushakashatsi byatanzwe na Suntory Health Co., Ltd., igurisha ibiryo byubuzima birimo LCPUFA.
Wechsler Logical Memory Scale II (WMS-R LM II) hamwe n'ikizamini cya Cognitive Montreal mu kiyapani (MoCA-J) cyakoreshejwe mugusuzuma.
Imyaka, igitsina, nuburere byanditswe nkibiranga abitabiriye amahugurwa. Amaraso yakusanyirijwe kuri baseline, ibyumweru 12 na 24 kugirango acide amavuta na LZ isesengura.
Igeragezwa rya Neuropsychologue ryakozwe kandi ibiryo bya fatty acide byapimwe kuri baseline, mubyumweru 12 na 24. Buri wese mu bitabiriye amahugurwa yarangije kwandika buri munsi, yandika ibyongeweho kandi agenzura impinduka zikomeye mu mibereho.
Ubushakashatsi bwerekanye ko LCPUFA + LZ nta ngaruka nini yagize ku mikorere yo kwibuka ku bageze mu za bukuru b'Abayapani bafite ibibazo byo kwibuka, ariko inyongera yazamuye imikorere yo kwibuka mu bitabiriye ubwenge bwo kugabanuka.
Abanditsi bavuga ko ubushakashatsi buzaza buzaza bushingiye ku bumenyi burambuye bw’imikorere y’ibanze y'abitabiriye amahugurwa bizafasha gufata imyanzuro ikwiye ku bijyanye n'ingaruka zo gutabara ku mikorere yo kwibuka.
“Ingaruka za aside irike ya polyunsaturated fatty acide ifatanije na lutein na zeaxanthin ku kwibuka episodic ku bantu bakuze bafite ubuzima bwiza”
Sueyasu, T., Yasumoto, K., Tokuda, H., Kaneda, Y.;
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