Acide Ellagic ni ibintu bisanzwe biboneka cyane cyane mu makomamanga. Ntabwo bitangaje, aside ellagic yamenyekanye cyane nkinyongera yimirire mumyaka yashize.

UwitekaUbushinwa Amakomamanga Ellagic Acideyahindutse imwe mu masoko akomeye ku isi ya aside ya ellagic, itanga inyongera yujuje ubuziranenge ihita iba igisubizo cyo guhitamo kubashaka kubungabunga ubuzima bwiza inzira karemano. Rivo ni amahitamo meza yo gutanga ikomamanga ikuramo aside ya ellagic.

Acide Ellagic ifite imikorere itandukanye ya bioactive, kandi hano turasesengura ibyiza bya acide ellagic n'impamvu igihingwa cy'amakomamanga cyitwa pomamanga ellagic acide gikundwa mubakunda ubuzima.

Antioxydeant ya acide ellagic

1 、 Gukata radicals yubuntu

Kuva mu myaka ya za 1950, antioxydeant ya aside ya ellagic muri vivo no muri vitro yakomeje gushakishwa no gukorwaho ubushakashatsi, kandi ibisubizo byinshi byubushakashatsi byagaragaje ko aside ellagic ifite imbaraga zikomeye zo gusiba no kwangiza antioxydeant. Acide Ellagic igira ingaruka zo gukata kuri ogisijeni ya ogisijeni na hydroxyl radicals, kandi ubushobozi bwayo bwo gusibanganya radicals yubusa ni bunini kuruta antioxydants nka sesquiterpene, ikibabi cya olive na luteolin.

2 、 Kubuza lipide peroxidation

Kubijyanye no kubuza lipide peroxidation, aside ellagic ifatwa nkigikorwa cyiza cyo gutangiza microsomal NADPH iterwa na lipide peroxidation iterwa na aside, kandi aside ellagic irashobora kandi kubuza cyane lipide peroxidisation iterwa na adriamycin. Acide Ellagic ibuza fer myoglobine / hydrogen peroxide iterwa na lipide peroxidation. Acide Ellagic irinda lipide peroxidation (LPO) iterwa nibintu bidasanzwe mu ngirabuzimafatizo za T, ikabuza ubwoko bwa ogisijeni ikora (ros) kandi ikanahindura imfu ziterwa na cytotoxine.

3 、 Ibindi bikorwa birwanya antioxydeant

Acide Ellagic irashobora kugabanya kwangirika kwingirabuzimafatizo ziterwa nimirasire, hydrogène peroxide na mitomycine C mumasemburo yimbeba. Acide Ellagic yabujije okiside ya DCDHF iterwa na peroxynitrite kimwe na okiside ya peroxynitrite ubwayo. Muri icyo gihe, aside ya ellagic yabujije peroxynitrite iterwa no kumeneka umurongo umwe wa pTZ 18U ya plasmid ADN hamwe na nitrasi ya matsinda ya tyrosinyl muri poroteyine yinyana. Rero, muri vitro, aside ellagic irinda biomolecules kwangirika kwa nitrite iterwa na okiside na nitrosative.

Ibindi bikorwa bya acide ellagic

Gukora pancreatic astrocytes nimpamvu yingenzi yibintu nka fibrosis pancreatic fibrosis na acute pancreatitis. Acide Ellagic ibuza interleukin 1b (IL-1) hamwe nikibyimba cya necrosis-α (TNF-α) -gukora poroteyine-1 hamwe na mitogen-ikora protein kinase, bityo bikabuza guhindura astrocytes ya pancreatic ivuka muri fenotipike ikora. Acide Ellagic ikora nka metabolite ya kabiri irwanya ibikorwa bya eosinofil muburyo bwa β-glucan peritonitis. Acide Ellagic ni inhibitori ya eosinofile kandi irashobora gukoreshwa mukuvura allergique. Acide Ellagic igira ingaruka za hepatoprotective kuko irwanya karubone tetrachloride iterwa na hepatotoxicity iterwa na vivo no muri vitro, kandi ikanarwanya tert-butyl hydroperoxide iterwa na lipide peroxidation.

Melanocytes iboneka murwego rwibanze rwa epidermis, ahakorerwa melanin. Ibikoresho fatizo byo gukora melanin ni tyrosine, bigomba guhindurwa bikurikiranye na tyrosinase muri dopa, dopaquinone hanyuma amaherezo melanine. Acide Ellagic ihagarika umusaruro wa melanin muguhagarika ibikorwa bya tyrosinase.

Kubwibyo rero, aside irike ya ellagic ikoreshwa cyane cyane nk'inyongeramusaruro mu miti ya farumasi, ibiryo byubuzima ndetse no kwisiga nkikintu gikora antioxydants, kurwanya virusi irwanya ubudahangarwa bw'umuntu, kwera uruhu, nibindi.

Kuki uhitamoUbushinwa Amakomamanga Ellagic Acide?

Ubushinwa bw'amakomamanga Ellagic Acide Uruganda rugenda rutanga isoko ryizewe kwisi, bitewe nibikoresho byiza byuburyo bwiza. Bateje imbere ubuhanga bwo gutanga inyongeramusaruro nziza, bareba ko ibicuruzwa byabo byujuje ubuziranenge bwumutekano ku isi. Nkigisubizo, inyongera ya acide ya ellagic itanga inyungu muri rusange nkubuzima bwiza bwo kurwanya inflammatory no kurwanya ibibyimba.

Mu gusoza, aside Ellagic ifite inyungu nyinshi kandi yishingikiriza ku mutekano wuzuye, wujuje ubuziranenge nkuwakozwe naUbushinwa Amakomamanga Ellagic Acideninzira nziza yo kubona ibipimo bihamye, byujuje ubuziranenge nta gushidikanya bifitiye akamaro ubuzima bwawe. Noneho, niba ushaka kugenzura ubuzima bwabantu no gukomeza ubuzima bwiza, tekereza kongeramo aside ya ellagic kubicuruzwa byawe uyumunsi.

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